An optimized semi-defined medium for p-coumaric acid production in extractive fermentation

نویسندگان

چکیده

In this study, the definition and optimization of a medium for cost-effective heterologous production as well efficient recovery plant secondary metabolite p-coumaric acid (p-CA) was performed. Experimental designs were carried out to end. First, Plackett Burman design used choose important factors that affect p-CA production. Then, central composite face centered find optima two major parameters, C/N ratio pH. Finally, four-component optimized semi-defined (OSD) developed experimented in both biphasic control batch fermentations. comparison results previous fermentations work using classic defined (a 2X Yeast Nitrogen Base without Amino Acids), OSD 10 times less expensive per litre. At pH 4.5, final approximately 61 % content reached medium. 6.0, 55 YNB

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

development and implementation of an optimized control strategy for induction machine in an electric vehicle

in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...

15 صفحه اول

Electro-extractive fermentation for efficient biohydrogen production.

Electrodialysis, an electrochemical membrane technique, was found to prolong and enhance the production of biohydrogen and purified organic acids via the anaerobic fermentation of glucose by Escherichia coli. Through the design of a model electrodialysis medium using cationic buffer, pH was precisely controlled electrokinetically, i.e. by the regulated extraction of acidic products with coulomb...

متن کامل

Title: an Extractive Fermentation Process for Enhanced Acetate Production from Biomass

Conventional fermentation technologies are limited due to low reactor productivity, low product yield, and low product concentration mainly due to product inhibition. There are several ways of improving the overall behavior of a biotechnological process. The cells can be modified so that the product is excreted prior to reaching inhibiting concentrations. Furthermore, a selective mutation of th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Process Biochemistry

سال: 2022

ISSN: ['1359-5113', '1873-3298']

DOI: https://doi.org/10.1016/j.procbio.2022.10.021